A weight reduction intervention in children with overweight and asthma
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Maartje Willeboordse1,6, Kim D.G. van de Kant1, Frans E.S. Tan2, Sandra Mulkens3, Julia Schellings4, Yvonne Crijns4, Liesbeth van de Ploeg5, Onno C.P. van Schayck6 and Edward Dompeling1
Aim There is increasing evidence that obesity is related to asthma development and severity. In children, it is largely unknown whether weight reduction contributes to improvements in asthma outcomes. We investigated the effects of a multifactorial weight reduction intervention on body weight and clinical asthma characteristics in children with asthma and overweight or obesity.
Methods An 18 month weight reduction RCT was conducted in 87 children with asthma and overweight or obesity. The intervention consisted of an intense programme with sport-, lifestyle-, parental- and individual sessions. Every 6 months, measurements of anthropometry, lung function, lifestyle parameters and inflammatory markers were assessed.
Discussion Our intervention demonstrated limited effects on both weight reduction and lung function. Possible reasons for the low effectiveness are high attrition rates, low intervention compliance, and weight reduction in the control group.
PDPI Jatim. 10/04/18.
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