Simonovska1 and Mirjana Trajcevska1
Tuberculosis, Institute for Lung Diseases and Tuberculosis, Skopje,
Macedonia, The Former Yugoslav Republic of
The purpose of this study
evaluate the importance of contact in the manifestation of
tuberculosis, ie what age, which forms manifest tuberculosis and what
is the time period from contact to manifestation of tuberculosis.
For this purpose, the histories of 88 cases of tuberculosis in persons
who have been in contact with tuberculosis, for the period 2010-2012.
The contact was comfirmed at 7.5% of analyzed TB patients.
47.7% were male and 52.3% were female. 28.4% belonged to the age group
of 0-14 years, 54.5% of the age group 16-44 years and 17% were older
than 44 years.
92% were with pulmonary, and 8% with extrapulmonary tuberculosis.
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of the Bacillus Calmette Guerin vaccination on clinical symptoms of
M. tuberculosis from sputum was isolated at 44.9%.
The source of infection in a close family member was in 76%. In 12%
source was another member of the family (grandmother, grandfather,
aunt). In 12% source was a roommate from the prisoner?s room,
or classmate or neighbor.
In 75%, the source of infection in the family was one of the parents,
in 15.6% was brother or siste, and at 9.4 % was one of the spouses.
Analyzing the time period for manifestation of tuberculosis after the
contact, in 56.7% tuberculosis is diagnosed to 3 months after the
contact, in 23.3% in a period of 3 to 6 months, and after 6 months
tuberculosis manifested in 20% of the respondents.
Conclusion: Contact was confirmed at 7.5% of analysed TB patients. In
76% of the cases source was in the family, and the most common source
was one of the parents (75.6%). After the contact tuberculosis usually
manifests in the first three months (56.7%). Because the tuberculosis
can manifest even after 6 months of contact, there is a need for
contact tracing in an extended period of time.