Sven-Arne Jansson1, Mai Leander2,
Linnea Hedman1, Malin Axelsson3, Caroline Stridsman4 and Eva
of Public Health and Clinical Medicine, Occupational and Environmental
Medicine, The OLIN Unit, Ume? University, Ume?,
Sweden, 2Department of Medical Sciences, Respiratory Medicine and
Allergology, Uppsala University, Uppsala, Sweden, 3Department of Care
Sciences, Faculty of Health and Society, Malm? University,
Malm?, Sweden, 4Department of Health Science, Division of
Nursing, Lule? University of Technology, Lule?,
burden of asthma and rhinitis on HRQL has been assessed mainly in
studies of patients seeking healthcare. Population-based studies are
Aim: To investigate
HRQL among subjects with asthma and rhinitis derived from a random
population sample and to identify factors related to impairment of HRQL.
Methods: A randomly
selected cohort was invited to participate in a postal questionnaire
survey. Of those who responded, a stratified sample of 1,000 subjects
was invited to clinical examinations and interviews, and 737 subjects
participated. HRQL was assessed with the generic item SF-36 Health
physical score was lower among subjects with asthma vs subjects without
asthma (p<0.001). No significant difference was found in the
mental score. Subjects with controlled asthma had higher physical score
compared to subjects with uncontrolled asthma (p=0.002). Actually,
subjects with controlled asthma had similar HRQL as subjects without
asthma. Asthmatics who were current smokers had lower physical score
compared to those who were not smokers (p=0.021). No significant
differences in physical or mental scores were found between subjects
with and without rhinitis. Subjects with both asthma and rhinitis had
lower physical score compared to subjects without these conditions
(p<0.001) but subjects with asthma alone had even worse physical
health. After adjustment for age, sex, smoking habits and BMI the
significant differences remained.
physical health was significantly lower in asthmatics and subjects with
both asthma and rhinitis compared to subjects without these conditions.
Importantly, subjects with controlled asthma had similar physical
health as subjects without asthma.
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